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Fluticasone Propionate+azelastine

About Fluticasone Propionate+azelastine

Azelastine+fluticasone Propionate belongs to the class of medications called 'anti-allergic' primarily used to treat allergic symptoms like sneezing, runny nose, congestion, stuffy nose, or watery eyes. An allergy is a condition that occurs when the immune system reacts to a foreign substance that is typically not harmful to your body. These foreign substances are known as ‘allergens.’ Allergic condition varies from person to person. Some might be allergic to certain foods and seasonal allergies like hay fever, pollen, or pet dander. One of the main symptoms of allergy is cough, and it acts as a reflex action in the throat when there is any mucus or foreign irritant entry into the respiratory system.

Azelastine+fluticasone Propionate is a combination of two drugs, namely: Fluticasone propionate (corticosteroid) and Azelastine (antihistamine/antiallergic). Fluticasone propionate belongs to the class of corticosteroids that works by acting inside cells of the nasal lining and stops the release of certain chemicals in the body that cause inflammatory reactions thereby relieving sneezing, runny or blocked nose, and sinus discomfort. On the other hand, Azelastine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness.

Use Azelastine+fluticasone Propionate as prescribed. Your doctor will recommend how often you take Azelastine+fluticasone Propionate based on your medical condition. Some people may experience headache, taste changes, or nose bleeds. Most of these side effects of Azelastine+fluticasone Propionate do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Azelastine+fluticasone Propionate or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Azelastine+fluticasone Propionate. Azelastine+fluticasone Propionate is not recommended for children below 6 years of age. If you experience any changes in vision, tiredness, nausea, vomiting, light-headedness, chills, fever, body pains, sores, redness or white patches in the mouth or throat, runny nose, severe nosebleeds, or increased drowsiness, stop taking Azelastine+fluticasone Propionate and consult a doctor immediately. Avoid contact with people who have infections or who are sick as Azelastine+fluticasone Propionate may weaken the immune system causing infections easily. If you have chickenpox, measles, tuberculosis, surgery or injury on the nose, glaucoma, cataracts, herpes infection of the eyes, ulcers or sores inside the nose, inform your doctor before taking Azelastine+fluticasone Propionate.

Uses of Fluticasone Propionate+azelastine

Allergic symptoms

Medicinal Benefits

Azelastine+fluticasone Propionate is a combination of two drugs, namely: Fluticasone propionate and Azelastine used to treat allergic symptoms such as sneezing, runny nose, congestion, stuffy nose, or watery eyes. Fluticasone propionate belongs to the class of corticosteroids that works by acting inside cells of the nasal lining. It stops the release of certain chemicals in the body that cause inflammatory reactions, thereby providing relief from sneezing, runny or blocked nose, and sinus discomfort. Azelastine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness. Together Azelastine+fluticasone Propionate relieves allergic symptoms, including seasonal allergies, and reduces inflammation of nasal passage.

Directions for Use

Use Azelastine+fluticasone Propionate as prescribed by your doctor. Check the label for directions before using Azelastine+fluticasone Propionate. Insert the tip of the bottle into a nostril while closing the other nostril and spray Azelastine+fluticasone Propionate towards the sides of the nostril. Keep your head straight and breathe gently. Repeat the same process for another nostril.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Fluticasone Propionate+azelastine

  • Headache
  • Taste change
  • Nose bleeds

Drug Warnings

If you are allergic to Azelastine+fluticasone Propionate or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Azelastine+fluticasone Propionate. Azelastine+fluticasone Propionate is not recommended for children below 6 years of age. If you experience any changes in vision, tiredness, nausea, vomiting, light-headedness, chills, fever, body pains, sores, redness or white patches in the mouth or throat, runny nose, severe nosebleeds, or increased drowsiness, stop taking Azelastine+fluticasone Propionate and consult a doctor immediately. Avoid contact with people who have infections or who are sick as Azelastine+fluticasone Propionate may weaken the immune system causing infections easily. If you have chickenpox, measles, tuberculosis, surgery or injury on the nose, glaucoma, cataracts, herpes infection of the eyes, ulcers or sores inside the nose, inform your doctor before taking Azelastine+fluticasone Propionate.

Drug Interactions

Drug-Drug Interaction: Azelastine+fluticasone Propionate may interact with antidepressants (duloxetine, escitalopram), anticonvulsants (pregabalin), HIV/AIDS drug (ritonavir), antifungals (ketoconazole, fluconazole, itraconazole) and anti-allergy drugs (cetirizine).

Drug-Food Interaction: Azelastine+fluticasone Propionate may interact with grapefruit juice. Therefore, avoid intake of grapefruit juice with Azelastine+fluticasone Propionate as it may lead to adrenal insufficiency and Cushing’s syndrome. Also, avoid consumption of alcohol with Azelastine+fluticasone Propionate as it may cause increased drowsiness, dizziness, impairment of judgement, and thinking.

Drug-Disease Interaction: If you have chickenpox, measles, tuberculosis, surgery or injury on the nose, glaucoma, cataracts, herpes infection of the eyes, ulcers or sores inside the nose, inform your doctor before taking Azelastine+fluticasone Propionate.

Drug-Drug Interactions Checker List:

  • DULOXETINE
  • ESCITALOPRAM
  • PREGABALIN
  • RITONAVIR
  • KETOCONAZOLE
  • FLUCONAZOLE
  • ITRACONAZOLE
  • CETIRIZINE
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consumption of alcohol with Azelastine+fluticasone Propionate as it may increase adverse effects. Please consult a doctor before consuming alcohol with Azelastine+fluticasone Propionate.

    • Safety Warning

      Pregnancy

      caution

      The safety of Azelastine+fluticasone Propionate in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks benefits outweigh risks.

    • Safety Warning

      Breast Feeding

      caution

      It is unknown whether Azelastine+fluticasone Propionate is excreted in human milk. It is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

    • Safety Warning

      Driving

      caution

      Azelastine+fluticasone Propionate may cause drowsiness in some people. Therefore, drive only if you are alert after taking Azelastine+fluticasone Propionate.

    • Safety Warning

      Liver

      safe if prescribed

      If you have any concerns regarding the use of Azelastine+fluticasone Propionate in patients with Liver problems, please consult a doctor.

    • Safety Warning

      Kidney

      safe if prescribed

      If you have any concerns regarding the use of Azelastine+fluticasone Propionate in patients with Kidney problems, please consult a doctor.

    • Safety Warning

      Children

      caution

      Azelastine+fluticasone Propionate is not recommended for children below 6 years as the safety and effectiveness were not established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Add ginger to foods or tea as it contains some anti-inflammatory compounds that can relax membranes in the airways and reduce cough, irritation and swelling in nasal passages.
    • Staying hydrated is vital for those with a cough or cold. Drink liquids at room temperature to get relief from a runny nose, cough, and sneezing.
    • The immune system is affected by stress and raises the risk of being sick. Do meditation, deep breathing, regular exercise and try progressive muscle relaxation techniques to get relief from stress.
    • It is advised to avoid contact with known allergens (allergy-causing agents) such as pollen, dust, etc. Certain food items are known to cause allergies to you.
    • Maintain personal hygiene and keep your surroundings clean.

    Special Advise

    Certain blood tests are recommended while taking Azelastine+fluticasone Propionate to monitor serum cortisol levels as Azelastine+fluticasone Propionate may increase these levels.

    Patients Concern

    Disease/Condition Glossary

    Allergy: It is a condition that occurs when the immune system reacts to a foreign substance that is typically not harmful to your body. These foreign substances are known as ‘allergens.’ Allergic condition varies from person to person. Some might be allergic to certain foods and seasonal allergies like hay fever, pollen, or pet dander. One of the main symptoms of allergy is cough, and it acts as a reflex action in the throat when there is any mucus or foreign irritant entry into the respiratory system.

    FAQs

    Azelastine+fluticasone Propionate contains Fluticasone propionate and Azelastine. Fluticasone propionate is a corticosteroid that works by acting inside cells of the nasal lining and stops the release of certain chemicals in the body that cause inflammatory reactions. Thereby, provides relief from sneezing, runny or blocked nose and sinus discomfort. Azelastine is an antihistamine (anti-allergic drug) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness.

    You are recommended to avoid taking grapefruit juice with Azelastine+fluticasone Propionate as they may lead to adrenal insufficiency and Cushing’s syndrome.

    No, you are not recommended to consume alcohol with Azelastine+fluticasone Propionate as it may cause increased drowsiness, dizziness, impairment of judgement and thinking. However, please consult a doctor before consuming alcohol with Azelastine+fluticasone Propionate.

    Azelastine+fluticasone Propionate is not recommended for children below 6 years as the safety and effectiveness were not established. However, please consult a doctor before using Azelastine+fluticasone Propionate in children.

    Yes, Azelastine+fluticasone Propionate may cause drowsiness in some people, especially in people consuming alcohol with Azelastine+fluticasone Propionate. It is not necessary for everyone taking Azelastine+fluticasone Propionate to experience this side effect. Therefore, avoid driving if you feel drowsy after taking Azelastine+fluticasone Propionate.

    You are not recommended to take more than the prescribed dose of Azelastine+fluticasone Propionate or for a prolonged time as it may cause adverse effects such as changes in body fat (especially in the back, waist, neck and face), easy bruising, skin thinning, increased facial hair or acne, loss of interest in sex, impotence or menstrual problems. However, if you experience any of these symptoms while taking Azelastine+fluticasone Propionate, please consult a doctor immediately.

    No, Azelastine+fluticasone Propionate is not used to treat asthma attacks. Azelastine+fluticasone Propionate is used to prevent allergic symptoms that can cause asthma. Therefore, it is recommended to carry a rescue inhaler always to treat asthma attacks.

    No, you are not recommended to stop taking Azelastine+fluticasone Propionate without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Azelastine+fluticasone Propionate for as long as your doctor has prescribed it, and if you experience any difficulty while taking Azelastine+fluticasone Propionate, please consult your doctor.

    You should avoid taking Azelastine+fluticasone Propionate and consult a doctor before using Azelastine+fluticasone Propionate if you have had any recent nose problems (like nose bleed, nose injury, nose ulcers, or nose surgery), infections like tuberculosis (TB), eye problems like herpes eye infection, glaucoma, or cataracts.

    Available Medicines for

    Fluticasone Propionate+azelastine

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